O potencial dos compostos polifenólicos das uvas para reduzir o stress oxidativo e a inflamação após o exercício: revisão sistemática
DOI:
https://doi.org/10.47197/retos.v64.110648Palavras-chave:
Uva, Inflamação, Stress oxidativo, Treino físico, Estilo de vida saudávelResumo
Introdução: O stress mecânico e a inflamação contribuem para o dano muscular induzido pelo exercício.
Objectivo: Esta investigação analisou o potencial dos compostos polifenólicos da uva para prevenir a inflamação e reduzir o stress oxidativo após o exercício.
Metodologia: Esta investigação utilizou uma revisão sistemática para orientar o investigador no logro dos objetivos. Implicou uma pesquisa exaustiva em bases de dados globais, como a Web of Science, Scopus, Embase e Pubmed. Os critérios de inclusão foram artigos que investigassem a uva, a inflamação, o stress oxidativo e o exercício físico praticado nos últimos cinco anos. Por outro lado, foram excluídos da pesquisa os artigos que não tinham boa reputação nem estavam indexados nestas bases de dados. O processo de pesquisa inicial gerou 2.947 artigos. Depois de realizar vários processos de seleção, por fim selecione e analise 8 artigos.
Resultados: Esta investigação mostra que o teor de polifenóis nas uvas tem propriedades antioxidantes e inflamatórias que podem reduzir os níveis de stress oxidativo e inflamatório.
Discussão: O conteúdo de polifenóis atua reduzindo os níveis de ERO, MDA e TBARS e aumentando os níveis de GSH. Além disso, as uvas também têm propriedades anti-inflamatórias que reduzem a inflamação descontrolada como consequência do exercício intenso. Neste caso, as uvas atuam bloqueando várias vias inflamatórias e diminuindo os marcadores inflamatórios. Os estudos in vivo também confirmaram estes benefícios anti-inflamatórios e antioxidantes para estimular a expressão do gene eNOS e aumentar os níveis de CAT, SOD e GPx4.
Conclusões: O teor de polifenóis na uva pode reduzir ambientalmente o stress oxidativo devido às suas propriedades antioxidantes. Além disso, as uvas têm propriedades anti-inflamatórias, que podem diminuir a inflamação descontrolada e aliviar a intensidade da dor muscular.
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Direitos de Autor (c) 2025 Novadri Ayubi, Atika Syafawi, Anton Komaini, Dhea Regita Sastika Putri, Ilham Ilham, Deby Tri Mario, Dyah Fitria Padmasari, Junian Cahyanto Wibawa; Procopio B. Dafun Jr.
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