Effects of HIIT vs. MICT on cardiorespiratory and metabolic function in clinical populations: systematic review and meta-analysis

Authors

  • David Ismael Ergas Schleef Saint Thomas Aquinas University
  • Soraya Jadue Arriaza Austral University of Chile
  • Yoselyn Yudith Reyes Sanchez Saint Thomas Aquinas University
  • Rocio Beatriz Bustos Barahona Saint Thomas Aquinas University
  • Mauro Ernesto Tauda Tauda Saint Thomas Aquinas University https://orcid.org/0009-0000-4864-3337

DOI:

https://doi.org/10.47197/retos.v72.116933

Keywords:

High-Intensity Interval training, moderate-Intensity continuous training, cardiorespiratory fitness, metabolic parameters

Abstract

Introduction: Structured physical training is a key tool in the prevention of cardiometabolic diseases. Two commonly used methods HIIT (high-intensity interval training) and MICT (moderate-intensity continuous training) have shown benefits, but their comparative effectiveness remains under investigation.

Objective: To compare the effects of HIIT versus MICT on VO₂max, blood pressure, and lipid profile in individuals at cardiovascular and metabolic risk, considering their applicability in various clinical populations.

Methods: A systematic search was conducted in five databases. Eight randomized controlled trials were included (n = 242). Risk of bias (RoB 2) and certainty of evidence (GRADE) were assessed. Fixed-effects models were applied.

Results: HIIT showed greater effectiveness than MICT across all variables. VO₂max improved by +1.57 ml/kg/min (95% CI: 1.02–2.12; p<0.001). Systolic blood pressure decreased by −4.30 mmHg and diastolic by −2.60 mmHg. Lipid profile improved: total cholesterol −6.70 mg/dL, LDL −6.60 mg/dL, triglycerides −8.70 mg/dL, and HDL +2.90 mg/dL. Heterogeneity was low (I² < 35%), and the certainty of evidence was high.

Conclusions: HIIT is more effective than MICT in improving cardiovascular and metabolic health, with consistent effects across different ages and clinical conditions.

Author Biographies

  • David Ismael Ergas Schleef, Saint Thomas Aquinas University

    Physical Education Teacher
    Diploma in Higher Education
    Master's in Physical Activity and Health

  • Soraya Jadue Arriaza, Austral University of Chile

    Physical Trainer
    Master in Physical Activity and Health

  • Yoselyn Yudith Reyes Sanchez, Saint Thomas Aquinas University

    Kinesiologist
    Master in Physical Exercise and Health

  • Rocio Beatriz Bustos Barahona, Saint Thomas Aquinas University

    Kinesiologist
    Master in Physical Exercise and Health

  • Mauro Ernesto Tauda Tauda, Saint Thomas Aquinas University

    Physical Trainer
    Physical Education Teacher
    Diploma in Exercise Physiology
    Master's in Clinical Exercise Physiology
    PhD Student in Physical Activity and Health, UNINI Mexico

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Published

04-09-2025

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Section

Theoretical systematic reviews and/or meta-analysis

How to Cite

Ergas Schleef, D. I., Jadue Arriaza, S., Reyes Sanchez, Y. Y., Bustos Barahona, R. B., & Tauda Tauda, M. E. (2025). Effects of HIIT vs. MICT on cardiorespiratory and metabolic function in clinical populations: systematic review and meta-analysis. Retos, 74, 993-1011. https://doi.org/10.47197/retos.v72.116933