The acute effects of Zone 2 aerobic exercise on Vagus nerve activity and postprandial sleepiness in women
DOI:
https://doi.org/10.47197/retos.v78.118411Keywords:
Zone 2 exercise, Heart rate variability, Vagus nerve, Postprandial somnolence, WomenAbstract
Background: postprandial sleepiness is a common problem in women, characterized by reduced alertness after meals due to autonomic and metabolic shifts toward digestion. Zone 2 aerobic exercise, a moderate-intensity activity focused on fat oxidation, may enhance vagal activity and counteract this postprandial sleepiness.
Objective: This study examined the acute effects of Zone 2 exercise on vagal activity and postprandial sleepiness in women.
Methods: Twenty women aged 30–45 years were randomly assigned to an experimental group (n=10) or a control group (n=10). After consuming a standardized meal, the experimental group performed 40 minutes of treadmill walking at Zone 2 exercise intensity (60–70% of maximum heart rate), while the control group rested passively. Vagal activity was assessed using heart rate variability (rMSSD values), and sleepiness was measured with the Stanford Sleepiness Scale. Paired and independent t-tests were used for analysis, with effect sizes calculated.
Results: The experimental group showed significant improvements, with increased rMSSD values and reduced sleepiness, whereas the control group demonstrated decreased vagal activity and increased sleepiness. Between-group post-test differences were statistically significant with large effect sizes.
Conclusion: Zone 2 exercise effectively enhances vagal tone and reduces postprandial sleepiness. It represents a practical, non-pharmacological strategy to improve alertness and autonomic balance in women.
References
Abdulghani, L. Y., Abdulghani, M. Y., & Abdulkareem, O. W. (2025). Designing a palm pressure meas-urement device to improve motor coordination in freestyle swimming among female students. Journal of Physical Education and Sport, 25(7), 1506-1513. https://doi.org/10.7752/jpes.2025.07168
Abdulkareem, O. W., & Sattar Jabbar, H. (2025). Comparative Biomechanical Analysis of Three-Point Shooting Between Elite Iraqi Basketball Players and International Counterparts. Journal of Sport Biomechanics. https://doi.org/10.61186/JSportBiomech.11.3.326
Barreto, A. C., Medeiros, A. P., da Silva Araujo, G., Vale, R., Vianna, J. M., Alkimin, R., ... & da Silva Novaes, J. (2023). Variabilidad de la frecuencia cardíaca y de la presión arterial durante y después de tres sesiones de CrossFit®(Heart rate variability and blood pressure during and after three Cross-Fit® sessions). Retos, 47, 311. https://doi.org/10.47197/retos.v47.93780
Basso, J. C., & Suzuki, W. A. (2016). The effects of acute exercise on mood, cognition, neurophysiology, and neurochemical pathways: a review. Brain Plasticity, 2(2), 127-152. https://doi.org/10.3233/BPL-160040
Buchheit, M., & Laursen, P. B. (2013). High-intensity interval training, solutions to the programming puzzle: Part I: cardiopulmonary emphasis. Sports medicine, 43(5), 313-338. https://doi.org/10.1007/s40279-013-0029-x
Colberg, S. R., Zarrabi, L., Bennington, L., Nakave, A., Somma, C. T., Swain, D. P., & Sechrist, S. R. (2009). Postprandial walking is better for lowering the glycemic effect of dinner than pre-dinner exer-cise in type 2 diabetic individuals. Journal of the American Medical Directors Association, 10(6), 394-397. https://doi.org/10.1016/j.jamda.2009.03.015
Diekmann, C., Wagner, M., Huber, H., Preuß, M., Preuß, P., Predel, H. G., ... & Egert, S. (2019). Acute im-pact of dietary pattern and walking on postprandial attention, mood, and satiety in older adults: a randomized crossover trial. Nutrients, 11(10), 2294. https://doi.org/10.3390/nu11102294
Easa, F. A. W., Shihab, G. M., & Kahdim, M. J. (2022). the Effect of Training Network Training in Two Ways, High Interval Training and Repetition To Develop Speed Endurance Adapt Heart Rate and Achieve 5000 Meters Youth. Revista Iberoamericana de Psicología Del Ejercicio y El Deporte, 17(4), 239-241.
Garcês, C. P., Silva, J. C., Sisconeto, T. M., Mariano, I. M., Cunha, A. C. R., Cheik, N. C., & Puga, G. M. (2025). Effects of acute aerobic and resistance exercise execution order on glycemia, blood pressure, and heart rate variability in postmenopausal women with type 2 diabetes mellitus: A random-ized controlled trial. Journal of Bodywork and Movement Therapies. https://doi.org/10.1016/j.jbmt.2025.05.009
Goodpaster, B. H., & Sparks, L. M. (2017). Metabolic flexibility in health and disease. Cell metabolism, 25(5), 1027-1036. https://doi.org/10.1016/j.cmet.2017.04.015
Hassan, A. (2025). The impact of CrossFit training on body composition, muscle strength, physiological adaptations, and the development of rebounding and footwork skills in basketball players. Re-tos, 70, 788-804. https://doi.org/10.47197/retos.v69.115399
Hassan, M. F. A., & Abdulkareem, O. W. (2025). Effects of an Integrated Balance and Muscle Tension Control Training Program on Kinematic Variables and Defensive Accuracy in Volleyball Players. Journal of Sport Biomechanics, 11(4), 438-464. https://doi.org/10.61882/JSPORTBIOMECH.11.4.438
Hassan, M. F. A., & Abdulkareem, O. W. (2025). The Effect of Mental Training on Psychological Hardi-ness and Selected Personality Traits among Adolescent Male Volleyball Players. International Journal of Exercise Science, 18(4), 1186. https://doi.org/10.70252/MQUH7716
Henson, J., Davies, M. J., Bodicoat, D. H., Edwardson, C. L., Gill, J. M., Stensel, D. J., ... & Yates, T. (2016). Breaking up prolonged sitting with standing or walking attenuates the postprandial metabolic response in postmenopausal women: a randomized acute study. Diabetes care, 39(1), 130-138. https://doi.org/10.2337/dc15-1240
Hottenrott, K., Ludyga, S., & Schulze, S. (2012). Effects of high intensity training and continuous endur-ance training on aerobic capacity and body composition in recreationally active runners. Jour-nal of sports science & medicine, 11(3), 483.
Hussain, F. M., Shuhaib, M. H., & Hassan, M. F. A. (2024). Psychological Toughness and its Relationship to Some Coordination, Physical Abilities and Accuracy of Some Basic Skills Performance Among The Iraqi Junior National Handball Team Players. International Journal of Disabilities Sports and Health Sciences, 7, 330-336. https://doi.org/10.33438/ijdshs.1436061
Kanai, T., & Teratani, T. (2022). Role of the vagus nerve in the gut-brain axis: Development and mainte-nance of gut regulatory T cells via the liver-brain-gut vago-vagal reflex. Brain and Nerve= Shinkei Kenkyu no Shinpo, 74(8), 971-977.
Kaneda, H., Kageyama, I., Kobayashi, Y., & Kodama, K. (2025). The Influence of Food Intake and Blood Glucose on Postprandial Sleepiness and Work Productivity: A Scoping Review. Nutrients, 17(20), 3217. https://doi.org/10.3390/nu17203217
Manickavelu, P., Subbaih, B., K, A., Baskaran, L. G., Kaliyaperumal, A. B., & Paneerselvam, S. (2025). En-hancing selective functional fitness among sedentary college students through functional loop resistance band training. Retos, 73, 1265-1276. https://doi.org/10.47197/retos.v74.117024
Orellana, C. S., Coria, G. D., Osorio, V. G., Dos Santos, A., & Roca, L. B. (2026). Relación de la variabilidad de la frecuencia cardiaca y el yo-yo test en deportistas universitarios. Retos, 75, 71-79. https://doi.org/10.47197/retos.v75.117688
Reynolds, A. N., Mann, J. I., Williams, S., & Venn, B. J. (2020). Advice to walk after meals is more effective for lowering postprandial glycaemia in type 2 diabetes mellitus than advice that does not speci-fy timing: A randomized crossover study. Diabetologia, 59(12), 2572-2578. https://doi.org/10.1007/s00125-016-4085-2
Saeed Mahmoud, S. M., Atia, D. T., Mostafa, D. S., Abdel-Latif, M. F., Fergany, L. A., Abdulrahman, N. M., Mohamed, K. E. S., & Elmahdy, M. A. (2025). Effect of cognitive-behavioral therapy combined with exercise training in adolescent girls with elevated depression symptoms: a randomized controlled clinical trial. Retos, 70, 1547-1557. https://doi.org/10.47197/retos.v70.116946
San-Millán, I., & Brooks, G. A. (2018). Assessment of Metabolic Flexibility in Elite Athletes and Individu-als with Type 2 Diabetes/Metabolic Syndrome. Sports Medicine, 48(2), 467-479. https://doi.org/10.1007/s40279-017-0751-x
Shaffer, F., & Ginsberg, J. P. (2017). An overview of heart rate variability metrics and norms. Frontiers in Public Health, 5, 258. https://doi.org/10.3389/fpubh.2017.00258
Soares-Miranda, L., Sattelmair, J., Chaves, P., Duncan, G. E., Siscovick, D. S., Stein, P. K., & Mozaffarian, D. (2014). Physical activity and heart rate variability in older adults: the Cardiovascular Health Study. Circulation, 129(21), 2100-2110. https://doi.org/10.1161/CIRCULATIONAHA.113.005361
Stanley, J., Peake, J. M., & Buchheit, M. (2013). Cardiac parasympathetic reactivation following exercise: implications for training prescription. Sports medicine, 43(12), 1259-1277. https://doi.org/10.1007/s40279-013-0083-4
Thayer, J. F., et al. (2012). A meta-analysis of heart rate variability and neuroimaging studies. Neuros-cience & Biobehavioral Reviews, 36(2), 747-756. https://doi.org/10.1016/j.neubiorev.2011.11.009
Valadez Jimenez, A., & González-Hernández, J. (2025). Correlation of sleep quality and chronotype on burnout in coaches. Retos, 68, 1339-1352. https://doi.org/10.47197/retos.v68.110935
Wang, X., Zheng, M., Qin, S., Li, Y., & Xu, H. (2025). Effects of aerobic vs combined aerobic and resistance exercise training on maternal glucose metabolism, sympathetic nervous system control and cardiovascular hemodynamics in women with overweight/obesity during pregnancy. Ginekologia Polska, 96(3), 184-191. https://doi.org/10.5603/gpl.102215
Zalillah, S. I., Jayadi, I., Andriana, L. M., Ashadi, K., Wiriawan, O., & Hariyanto, A. (2025). Total-body aer-obic gymnastic exercises more effective than low intensity steady state to improving body composition in adult women with sedentary. Retos, 68, 2031-2041. https://doi.org/10.47197/retos.v68.113196
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